Luwes Cream is a medicine that contains a combination of medicines that is used to treat melasma. It helps in quick skin renewal. It provides relief from redness, swelling, and itching. Luwes Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies to this medicine. Key Ingredients Hydroquinone (2% w/w) + Tretinoin (0.025% w/w) + Fluocinolone acetonide (0.01% w/w) How to use Luwes Cream This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area. How Luwes Cream works Luwes Cream is a combination of three medicines: Hydroquinone, Tretinoin and Fluocinolone acetonide which treat melasma (dark spots on skin). The exact way this triple combination improves melasma is not fully known. Hydroquinone helps reduce melanin (skin pigment), tretinoin promotes skin cell turnover, and fluocinolone acetonide reduces skin inflammation.